Customization: | Available |
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CAS No.: | 98-59-9 |
Formula: | C7h7clo2s |
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Melting point | 65-69 °C(lit.) |
Boiling point | 134 °C10 mm Hg(lit.) |
Density | 1,006 g/cm3 |
Vapor pressure | 1 mm Hg ( 88 °C) |
RTECS | DB8929000 |
Fp | 128 °C |
Storage temp. | Store below +30°C. |
Form | Crystalline Powder |
Color | White |
Core uses of Tosyl chloride:
1. Organic synthesis field
Sulfonylation reaction:
Reacting with alcohols, phenols, and amines to form sulfonic acid esters (protecting hydroxyl groups) or sulfonamides (protecting amino groups), widely used in the preparation of organic intermediates;
Participate in the epoxidation reaction of 1,2-diol and the conversion of allyl alcohol to allyl chloride.
Selective modification:
Selective control of O - or N-sulfonylation can be achieved by adjusting solvents such as pyridine or triethylamine;
Promote Beckmann rearrangement reaction to generate lactam compounds.
2. Analytical Chemistry Applications
Derivative reagents:
Reacting with hydroxyl/amino compounds to generate easily detectable derivative products for GC-MS, HPLC-MS analysis of drugs, pesticides, and food ingredients;
Detecting drug impurities or preparing stable compounds (such as quality control reagents).
3. Pesticide Industry
Drug synthesis:
Synthesis of sulfonamide drugs (such as metoclopramide), antibiotics, and anticancer drug intermediates;
Pesticide production:
Prepare herbicides (such as metoclopramide) and fungicides (such as metoclopramide).
4. Dyes and Fine Chemicals
Dye intermediates:
Introducing sulfonic acid groups for dispersing dyes, ice dyes, and acid dyes;
Molecular rearrangement reactions involved in hormone synthesis.
5. Polymer materials industry
Aggregation modification:
As an initiator or crosslinking agent for polymerization reactions, used for polymer functionalization modification;
The precursor for synthesizing sulfonated polymer materials.
6. Other industrial applications
Surfactants/Plasticizers: Synthetic industrial surfactants, plasticizers, and lubricants;
Preparation of fine chemicals: used for the synthesis of organic compounds such as ketones, esters, amides, etc.
P-Toluene sulfonyl chloride (PTSC) is a white crystalline powder. It has a minimum purity of 99% and a melting point not lower than 67ºC. The maximum water content is 0.05%, and the colority (APHA) should not exceed 20. The maximum content of free acid is 0.3%, and the maximum content of o-toluene sulfonyl chloride (OTSC) is 0.2%.
PTSC is an important organic compound with wide applications in the chemical and industrial fields. It is commonly used in the synthesis of dyes, and high-molecular-weight materials. PTSC exhibits excellent chemical stability and reactivity, making it a valuable raw material for synthesizing intermediates and functional materials.
FAQ:
Q1: Can I get samples?
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Q3: How is your MOQ?
A: Normally speaking, our MOQ is 1kg. But we can also accept less quantity such as 100g on the condition that sample charge is100% paid.
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1. Our staff are all experienced in chemical products or related major background, they are well trained before quotation.
2. Free sample or pre-shipment sample are available for our new cooperation before you place commercial order. We are sure the same specification commercial products as sample to customers
3. Third Party Inspection like SGS can be arranged according to your requirement before shipping.
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