| Customization: | Available |
|---|---|
| CAS No.: | 723-46-6 |
| Type: | The First Class |
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| Item | Test Standard | Testing Result | |
| Appearance | Powder | Complies | |
| Color | White fine Powder | Complies | |
| Particle Size | 100% pass 80 mesh | Complies | |
| Oder | Characteristic | Complies | |
| Taste | Characteristic | Complies | |
| Loss on Drying | ≤5.0% | 2.20% | |
| Residue on Ignition | ≤0.1% | 0.05% | |
| Heave Mentals | ≤10ppm | Complies | |
| Na | ≤0.1% | <0.1% | |
| Pb | ≤3 ppm | Complies | |
| Total Plate | <1000CFU/g | Complies | |
| Yeast & Mold | <100 CFU /g | Complies | |
| E. Coli | Negative | Complies | |
| Salmonella | Negative | Complies | |
| Conclusion: Conform with USP Standard | |||
Description:
Rebeprazole sodium was launched as Pariet in Japan, its first market, for the treatment of peptic ulcers including gastric and duodenal ulcers. From 4-chloro- 2,3-dimethylpyridine N-oxide, a six step synthesis allows access to the basic skeleton after successive condensations. Rabeprazole, a structural analog of Omeprazole, the first compound to have been marketed in this class up to now, is reported to be a more potent inhibitor of gastric H+/K+-adenosine triphosphate (ATPase) ; a common mechanism of action of this chemical class involves the conversion at low pH to a reactive sulphonamide that itself binds to cysteine residues located on the enzyme. Moreover, rabeprazole showed an antibacterial activity against Helicobacter Pylori, with a MIC90 of 1.56 μg/ml.
Rebeprazole sodium has a faster onset of action compared with omeprazole, but a shorter duration of action, being extensively and rapidly metabolized in several animal species. In clinical studies in patients with gastric ulcers, 10 and 20 mg rabeprazole sodium once-daily significantly inhibited basal and stimulated acid output. Rabeprazole is awaiting registration in the US for treatment of gastrooesophageal reflux disease (GORD) and other pathologic hypersecretory conditions including Zollinger-Ellison syndrome.
It belongs to national second-class drug that can be used for the treatment of gastric ulcer. It can be used for the treatment of peptic ulcer, gastroesophageal reflux disease, zollinger-ellison syndrome and other diseases.
FAQ:
Q1: Can I get samples?
A: Yes, we can provide you with free samples, but the freight needs to be paid by you, I hope you can understand.
Q2: How to pay?
A: PI will be sent firstly after our aligned products specification. Payment by Paypal , T/T, Western Union,LC, are ok.
Q3: How is your MOQ?
A: Normally speaking, our MOQ is 1kg. But we can also accept less quantity such as 100g on the condition that sample charge is100% paid.
Q4: How can you guarantee the quality of your products ?
1. Our staff are all experienced in chemical products or related major background, they are well trained before quotation.
2. Free sample or pre-shipment sample are available for our new cooperation before you place commercial order. We are sure the same specification commercial products as sample to customers
3. Third Party Inspection like SGS can be arranged according to your requirement before shipping.
4. On-Spot QC in our APPROVED associated production bases with necessary certification like GMP, ISO etc.
Q5:How is your after-sales service?
A: If you have any technical or quality problems after receiving the goods, you can always contact us. If the problem is caused by us, we will send you the goods for free or refund your loss.
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