| Customization: | Available |
|---|---|
| CAS No.: | 177325-13-2 |
| Type: | The First Class |
|
Still deciding? Get samples of $ !
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| Product name | Levofloxacin hydrochloride CAS 177325-13-2 |
| Appearance | White crystalline powder |
| MF | C18H20FN3O4.HCl |
| Assay | HPLC 99% |
| Shelf Life | 2 years |
| Storage | Keep in cool dry place |
Function:
Levofloxacin is used to treat infections including: respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, endocarditis, meningitis, pelvic inflammatory disease, traveler's diarrhea, tuberculosis, and plague and is available by mouth, intravenously,and in eye drop form.
Levofloxacin is used for the treatment of pneumonia, urinary tract infections, and abdominal infections. As of 2007 the Infectious Disease Society of America (IDSA) and the American Thoracic Society recommended levofloxacin and other respiratory fluoroquinolines as first line treatment for community acquired pneumonia when co-morbidities such as heart, lung, or liver disease are present or when in-patient treatment is required.Levofloxacin also plays an important role in recommended treatment regimens for ventilator-associated and healthcare-associated pneumonia.
As of 2010 it was recommended by the IDSA as a first-line treatment option for catheter-associated urinary tract infections in adults.In combination with metronidazole it is recommended as one of several first-line treatment options for adult patients with community-acquired intra-abdominal infections of mild-to-moderate severity.The IDSA also recommends it in combination with rifampicin as a first-line treatment for prosthetic joint infections.The American Urological Association recommends levofloxacin as a first-line treatment to prevent bacterial prostatitis when the prostate is biopsied.and as of 2004 it was recommended to treat bacterial prostatitis by the NIH research network studying the condition.
Levofloxacin and other fluoroquinolones have also been widely used for the treatment of uncomplicated community-acquired respiratory and urinary tract infections, indications for which major medical societies generally recommend the use of older, narrower spectrum drugs to avoid fluoroquinolone resistance development. Due to its widespread use, common pathogens such as Escherichia coli and Klebsiella pneumoniae have developed resistance. In many countries as of 2013, resistance rates among healthcare-associated infections with these pathogens exceeded 20%.
Levofloxacin is also used as antibiotic eye drops to prevent bacterial infection. Usage of levofloxacin eye drops, along with an antibiotic injection of cefuroxime or penicillin during cataract surgery, has been found to lower the chance of developing endophthalmitis, compared to eye drops or injections alone.
Application:
Levofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Like all quinolones, it functions by inhibiting the two type II topoisomerase enzymes, namely DNA gyrase and topoisomerase IV. Topoisomerase IV is necessary to separate DNA that has been replicated (doubled) prior to bacterial cell division. With the DNA not being separated, the process is stopped, and the bacterium cannot divide. DNA gyrase, on the other hand, is responsible for supercoiling the DNA, so that it will fit in the newly formed cells. Both mechanisms amount to killing the bacterium. In this way, levofloxacin acts as a bactericide.
FAQ:
Q1: Can I get samples?
A: Yes, we can provide you with free samples, but the freight needs to be paid by you, I hope you can understand.
Q2: How to pay?
A: PI will be sent firstly after our aligned products specification. Payment by Paypal , T/T, Western Union,LC, are ok.
Q3: How is your MOQ?
A: Normally speaking, our MOQ is 1kg. But we can also accept less quantity such as 100g on the condition that sample charge is100% paid.
Q4: How can you guarantee the quality of your products ?
1. Our staff are all experienced in chemical products or related major background, they are well trained before quotation.
2. Free sample or pre-shipment sample are available for our new cooperation before you place commercial order. We are sure the same specification commercial products as sample to customers
3. Third Party Inspection like SGS can be arranged according to your requirement before shipping.
4. On-Spot QC in our APPROVED associated production bases with necessary certification like GMP, ISO etc.
Q5:How is your after-sales service?
A: If you have any technical or quality problems after receiving the goods, you can always contact us. If the problem is caused by us, we will send you the goods for free or refund your loss.
){kind=link}