Wholesale Pharma Estradiol Valerate Hormone Raw Powder CAS 50-28-2 Beta-Estradiol DDP Fast Shipping

Product Description

Product Description

 

1. Basic Information

Item	Details
Product Name	17β - Estradiol (E2)
Alternate Names	17β - oestradiol; Estradiol; 1,3,5 - estratriene - 3,17β - diol
CAS Number	50 - 28 - 2
Molecular Formula	C18H24O2
Molecular Weight	272.38
IUPAC Name	estra - 1,3,5(10) - triene - 3,17β - diol
Purity	≥98% (HPLC)
Appearance	White to off - white crystalline powder

2. Physicochemical Properties

Property	Specific Content
Melting Point	176 - 180 °C (lit.)
Boiling Point	Approximately 445.9 °C at 760 mmHg
Density	About 1.2 g/cm³ (predicted)
Solubility	Soluble in DMSO (54 mg/ml at 25°C), ethanol (23 mg/ml at 25°C); slightly soluble in vegetable oils; insoluble in water (<1 mg/ml)
Refractive Index	n20/D 1.60 (predicted)
Optical Activity	α20/D + 76.8°, c = 1 in dioxane

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3. Biological Characteristics

Item	Details
Target Receptors	Endogenous estrogenic hormone receptor (ER) agonist; high - affinity ligand for membrane estrogen GPR30 receptors
Binding Affinity	Ki values are 0.12 nm for ERα and 0.13 nm for ERβ respectively
Biological Activity	Acts as an activator of PI3 - kinase; upregulates IL - 6 expression through the estrogen receptor β (ERβ) pathway; induces nitric oxide synthase in the aorta
IC50 Values	0.01 nm for human estrogen receptor; 0.1 nm for human SK - BR - 3 cells; 0.32 nm for human MCF 7 cells

4. Packaging & Storage

Packaging Specification	Details
Common Packages	1g, 5g, 20g, 100g in glass bottles
Storage Conditions	Store at 2 - 8 °C for long - term preservation; avoid direct sunlight and moisture. After reconstitution into stock solution with DMSO, store at 4 °C in de - gassed containers, which can remain stable for up to 6 months.
Shelf Life	3 years from the production date when stored according to the recommended conditions.

 
 
 

5. Application Fields

1. Scientific Research: Widely used in cell biology and molecular biology experiments, such as studying the regulatory mechanism of estrogen receptors in cell proliferation and differentiation. It is applicable to cell lines like HCC1806, MCF 7 for in - vitro experiments, and can be used in female Sprague - Dawley rats for in - vivo studies.
2. Pharma R&D: Serves as a key raw material for researching hormone replacement therapy drugs, used to develop preparations for relieving menopausal symptoms such as hot flashes and vaginal dryness.
3. Biochemical Analysis: Acts as a standard substance in HPLC and other analytical methods for the detection of estrogen content in biological samples and pharma products.

 

Detailed Photos

 

Packaging & Shipping

 
 

Company Profile

 

Hubei Highwin New Material Technology Co., Ltd. focuses on the research and development, production and sales of epoxy resin and other chemical raw materials.

We have our own R&D laboratory, by ordinating our suppiers all over the world and manufacturing products with cooperated based factories, we're keeping enhance our competitiveness in the market.
Before developing overseas sales, we have been rooted in chemical raw materials for more than 20 years and have already been one of the top suppliers in China after years of efforts.

There are a group of hard-working, motivated, and creative staff working not only for the company but also for you--our respectable customer and partner! Based on good service and high-quality products, we're widely praised and trusted by customers and keep long-lasting relationships with them.
 

R&D Center

 

FAQ

Q:How to get a sample, is it free?

A:You can contact our sales staff through REQUEST and they will arrange sample shipment for you. We can provide you with free samples, you only need to pay for the shipping cost. For regular customers, sample fee and shipping fee are covered by us!

Q:How can I trust you? How long have you been in this field(Chemical raw material)?

A:Our owner has over 20 years of experience in the chemical raw materials field as well as our staffs. It is because of the trust of our customers and partners that we have been able to exist and develop for so many years. Our ever-lasting vision is to 'Obtain a wide range of customer resources through high-quality procurement and the best service, and establish a sustainable and stable customer relationship'!

Q: Can you offer any other services?

A:Yes! If you learn that there are very competitive products in China that are not within the scope of our display, we'd love to help you find quality resources. It's our honor to provide a one-stop purchasing service for you!

Q:How do you guarantee the quality of your products?

A:All of our products comply with national testing standards and international standards. If you need, we can provide you with certificates.

Q: Can you use customer-specific labeling and packaging?

A: Of course, you can provide us with the specified labeling and packaging and we will be happy to follow up with you.assist you. If there is anything else you need, please feel free to communicate with us!

Q: How about the delivery time?

A: We can’t give you the exact time because of different locations, but we can guarantee that we will ship your order as soon as possible after you place it and we will keep an eye on the logistics to remind you to receive the goods.