| Customization: | Available |
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| CAS No.: | 110-85-0 |
| Formula: | C4h10n2 |
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Piperazine is an organic compound with the chemical formula C4H10N2. It is a colorless crystal with the smell of ammonia and is highly hygroscopic. The melting point of piperazine is 109.6ºC, the boiling point is 148.5ºC, and the molecular weight is 86.14. It is easily soluble in water, methanol, and ethanol, slightly soluble in benzene and ether, and is corrosive. It is flammable when exposed to open flames and high temperatures, and releases toxic nitrogen oxide gas when it burns and decomposes. Piperazine absorbs moisture and carbon dioxide in the air. Its phosphate and citrate are effective drugs for expelling roundworms and pinworms, so it is also called roundworm expelling spirit. In addition, piperazine can also be prepared from chloroethanol by ammoniation and cyclization, and is an important pharmaceutical intermediate. 12.
The application of piperazine is not limited to the field of medicine. It is also widely used in the production of anthelmintic drugs such as piperazine phosphate and piperazine citrate, as well as fluphenazine, chlorphenamine, etc. Piperazine hexahydrate is a chemical substance with a molecular formula of C4H22N2O6. It is mainly used to produce surfactant products such as wetting agents, emulsifiers, dispersants, as well as antioxidants, preservatives, stabilizers, plastic processing aids and rubber additives, etc. 3.
In the field of medicine, piperazine and its derivatives exhibit a variety of pharmacological effects. For example, piperazine ferulate tablets have anti-platelet aggregation, vasodilator, and antioxidant effects, and are used to treat cardiovascular and cerebrovascular diseases, improve microcirculatory disorders, and protect the nervous system, etc. 4. In addition, piperazine is also classified as an anticholinergic drug, used to treat mild infections and improve symptoms caused by gastrointestinal dysfunction, such as abdominal pain, diarrhea, etc.
| Melting point | 109-112 °C(lit.) |
| Molecular formula | C4H10N2 |
| Molecular weight | 86.136 |
| Flash point | 49.7±10.2 °C |
| Exact mass | 86.084396 |
| PSA | 24.06 |
| LogP | -1.17 |
| Appearance | Needle-shaped white or colorless crystals |
| Vapor pressure | 4.0±0.3 mmHg at 25°C |
| Refractive index | 1.424 |
| Storage conditions | Store in a cool, dry, well-ventilated warehouse. Keep away from fire and heat sources. Keep the container sealed. Store separately from oxidants, acids, etc. and avoid mixing. Equip with fire-fighting equipment of corresponding types and quantities. The storage area should be equipped with appropriate materials to contain leaks. |
| Stability | Avoid contact with humid air and direct sunlight. Do not contact with strong oxidants, strong acids, acid chlorides, and acid anhydrides. |
| Water solubility | 150 g/L (20 ºC) |
| Molecular structure | 1. Molar refractive index: 25.14 |
| 2. Molar volume (cm3/mol): 98.5 | |
| 3. Isotonic volume (90.2K): 225.8 | |
| 4. Surface tension (dyne/cm): 27.5 | |
| 5. Polarizability (10-24cm3): 9.96 |
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