Manufacturer Supply 16- (Tert-butoxy) -16-Oxohexadecanoic Acid CAS 843666-27-3 Fast Shipping Sample Available

• Customization: Available
• CAS No.: 843666-27-3
• Formula: C20h38o4
• Shipping Term: Negotiated
• Payment Term: Negotiated
• Transport Package: Bags
• Specification: 25kg/bag
• Origin: China
• HS Code: 2918990090
• Production Capacity: 60000/Year

Product Description

Product Description

Hexadecyl diacid mono-tert-butyl ester (Boc-C14-C0OH) is an important chemical substance, mainly used in the synthesis of antibody drug conjugates (ADC) and PROTAC linkers.
Basic information
Chemical formula: C20H3804 Molecular weight: 341.50500
Appearance: White off-white crystals-powder Melting point: 58.0-62.0°C
Density: 0.959±0.06g/cm3
Solubility: Insoluble in water (2.9E-3 g/L at 25°C) 12 Uses
ADC linker: Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody drug conjugates (ADC). ADC consists of antibodies connected to cytotoxins through ADC linkers for cancer treatment12.
PROTAC linker: Boc-C14-C00H is also an alkyl chain-based PROTAC linker used in the synthesis of PROTAC. PROTAC promotes the degradation of target proteins by simultaneously connecting the target protein and the ubiquitin ligase system12. Preparation method
The preparation of Boc-C14-COOH is usually carried out by the anhydride method, which includes esterification of hexadecanoic acid with anhydride acid, and then adding tert-butyl alcohol for alcoholysis to obtain the final Boc-C14-C00H product4.

Storage conditions
Boc-C14-COOH should be stored at room temperature.


 

Product Parameters

 

Density	0.959±0.06 g/cm3
Melting point	58.0-62.0°C
Molecular formula	C20H38O4
Molecular weight	341.505
Exact mass	341.269
PSA	66.43
LogP	4.5394
Appearance	White off-white crystals-powder
Storage conditions	Room temperature
Water solubility	Insuluble (2.9E-3 g/L) (25 ºC)

 

 

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Company Profile

 

Hubei Highwin New Material Technology Co., Ltd. focuses on the research and development, production and sales of epoxy resin and other chemical raw materials.

We have our own R&D laboratory, by ordinating our suppiers all over the world and manufacturing products with cooperated based factories, we're keeping enhance our competitiveness in the market.
Before developing overseas sales, we have been rooted in chemical raw materials for more than 20 years and have already been one of the top suppliers in China after years of efforts.

There are a group of hard-working, motivated, and creative staff working not only for the company but also for you--our respectable customer and partner! Based on good service and high-quality products, we're widely praised and trusted by customers and keep long-lasting relationships with them.
 

R&D Center

 

FAQ

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A:Our owner has over 20 years of experience in the chemical raw materials field as well as our staffs. It is because of the trust of our customers and partners that we have been able to exist and develop for so many years. Our ever-lasting vision is to 'Obtain a wide range of customer resources through high-quality procurement and the best service, and establish a sustainable and stable customer relationship'!

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