Customization: | Available |
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CAS No.: | 97-18-7 |
Formula: | C12h6cl4o2s |
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The chemical composition of Bithionol is 2,2′-dihydroxy-3,3′,5,5′-tetrachlorodiphenyl sulfide, with a molecular formula of C12H6Cl4O2S and a molecular weight of 356.0512. Bithionol is white or off-white powder, odorless or slightly phenolic, with a melting point of 186°-189°C. It is easily soluble in acetone, alcohol and ether, soluble in chloroform and dilute caustic soda solution, and insoluble in water.
Chemical properties
Bithionol has antibacterial effects and can inhibit the growth and reproduction of bacteria. In addition, it also has insecticidal effects and is mainly used clinically to treat paragonimiasis, beef tapeworm disease and ginger fasciculosis.
Physical properties
The density of thiobisdichlorophenol is 1.8±0.1 g/cm³, the boiling point is 444.7±45.0°C at 760 mmHg, and the flash point is 222.8±28.7°C.
Preparation method
The preparation method of thiobisdichlorophenol involves chemical reactions, and the specific steps are relatively complicated, usually requiring a professional chemical laboratory to operate. Its preparation process includes multiple chemical reaction steps, and finally obtains the target compound.
Uses
Thiobisdichlorophenol is mainly used in medicine to treat paragonimiasis, beef tapeworm disease and ginger fasciococcus. Its medication method varies according to different diseases. For example, for paragonimiasis and clonorchiasis, the full daily dose can be taken in 3 times, every other day, and the total treatment course is 30-45g; for ginger fasciococcus, 2-3g of the drug can be taken once on an empty stomach before going to bed.
Density | 1.8±0.1 g/cm3 |
Boiling point | 444.7±45.0 °C at 760 mmHg |
Melting point | 188°C |
Molecular formula | C12H6Cl4O2S |
Molecular weight | 356.052 |
Flash point | 222.8±28.7 °C |
Exact mass | 353.884247 |
PSA | 65.76 |
LogP | 5.51 |
Appearance | White or light gray-white, crystalline powder, odorless or with a light aromatic or phenolic odor |
Vapor pressure | 0.0±1.1 mmHg at 25°C |
Refractive index | 1.741 |
Storage conditions | 0-6°C |
Stability | White crystalline powder, easily soluble in ethanol, acetone, soluble in dilute alkali solution, insoluble in water. This product is low in toxicity and has almost no irritation to the skin. |
Water solubility | <0.1 g/100 mL at 23 ºC |
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