Customization: | Available |
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CAS No.: | 306-67-2 |
Formula: | C10h30cl4n4 |
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Spermine Tetrahydrochloride is a chemical substance with the chemical formula C10H26N4.4ClH, a molecular weight of 348.18, and a CAS registration number of 306-67-212. It is a polyamine compound with multiple amino groups and is involved in a variety of biological processes, including DNA replication, transcription, and translation.
Chemical properties
The melting point of spermine tetrahydrochloride is 310-311°C, the density is 1.01 g/mL (20°C), the water solubility is 348.2 g/L (20°C), and the morphology is white to nearly white powder24. Its pH value is 4.5-7.0 (25°C, 1M in H2O), and the maximum absorption wavelengths are 260 nm and 280 nm, respectively.
Biological activity
Spermine tetrahydrochloride is an endogenous metabolite with multiple biological activities. It is able to stabilize DNA structure by binding to the negatively charged phosphate groups of DNA, neutralizing the charge and promoting the formation of a stable and compact DNA structure, which is essential for correct DNA packaging and organization, ultimately affecting gene expression and cell function. In addition, spermine tetrahydrochloride is also involved in the regulation of enzyme activity, interacting with enzymes, changing their structure or catalytic activity, maintaining cell homeostasis and ensuring the normal functioning of enzyme pathways. It also plays a role in cell signaling and membrane stability, interacting with phospholipids, the main component of cell membranes, maintaining the integrity of cell membranes and regulating the transport of molecules in and out of cells.
Application areas
As an important bioactive substance, spermine tetrahydrochloride is widely used in scientific research, dietary supplements, and potential biomedical applications. It has also been studied for its antibacterial properties and has inhibitory effects on a variety of microorganisms.
Density | 1.01 g/mL at 20 °C |
Boiling point | 308.4ºC at 760mmHg |
Melting point | 310-311 °C (dec.)(lit.) |
Molecular formula | C10H30Cl4N4 |
Molecular weight | 334.157 |
Flash point | 175.6ºC |
Exact mass | 332.106812 |
PSA | 76.1 |
LogP | 5.0338 |
Appearance | powder |
Storage conditions | Seal with argon and store in a dry place below 0ºC away from light |
Water solubility | H2O: 1 M at 20 °C, clear, colorless |
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